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Crossword solution:
O
C
T
O
12 clues for "OCTO":
Eight (prefix)
Eight: Comb. form
Numerical combining form
Numerical prefix
Duo quadrupled
Eight: pref.
Prefix for -pus
Prefix meaning "eight"
Prefix with mom
Prefix with 'mom' in 2009 news
Prefix with -pod
Tetra- doubled