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Crossword solution:

46 clues for "NIECE":

  1. She may cry uncle
  2. Elizabeth II to Edward VIII.
  3. One who cries 'Uncle!' (wordplay)
  4. Princess Anne, to Margaret
  5. Dorothy to Em
  6. Family member
  7. Female relative.
  8. Girl who cries uncle
  9. One who cries "Uncle"
  10. Princess Anne to Princess Margaret
  11. Relative.
  12. Sibling's daughter
  13. Sister's daughter.
  14. Son's cousin.
  15. A family-tree apple
  16. Agnes, to Cecil B.
  17. Amy Carter, to Billy
  18. Amy, to Billy
  19. Anne to Margaret Rose.
  20. Beatrice, to Leonato, in 'Much Ado About Nothing'
  21. Brother's child
  22. Brother's daughter
  23. Caroline, to Edward Kennedy
  24. Caroline, to Sen. Kennedy
  25. Caroline, to Ted
  26. Caroline, to Teddy
  27. Caroline to Ted Kennedy
  28. D.J., Stephanie or Michelle, to Jesse, on 'Full House'
  29. Dorothy Gale to Em
  30. Electra to Menelaus
  31. Family-reunion attendee
  32. Houghton to Hepburn
  33. Iphigenia, to Menelaus
  34. Kathleen Kennedy Townsend, to JFK
  35. Kinswoman
  36. Member of the family
  37. Morticia to Fester on The Addams Family
  38. Nephew's sib
  39. Nephews sister
  40. One's brother's daughter
  41. One who says "uncle"
  42. Relation
  43. Shes more than nice
  44. Sisters child
  45. Uncle's favorite.
  46. Whitney, to Dionne