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Crossword solution:

20 clues for "CANIS":

  1. ___ Major or Minor.
  2. ___ Major.
  3. Dog genus.
  4. Major or Minor constellation.
  5. ___ Major (southern constellation)
  6. Animal genus
  7. Celestial dog.
  8. Constellation ___ Major.
  9. Dog: Lat.
  10. Fido's genus
  11. Fido, to Cato
  12. Genus of dogs.
  13. Major constellation
  14. ___ Major, constellation of the Dog Star.
  15. Major Dog Stars locale
  16. ___ Major, locale of Sirius
  17. ___ Major, near Orion.
  18. ___ Major, Sirius' constellation
  19. ___ Major (Sirius's constellation)
  20. ___ Minor.